Hemochromatosis is a genetic disorder that increases iron absorption in the body. Excess iron accumulates in the body over time, leading to tissue and organ damage. We are unable to excrete excess iron, hence it must be removed by regular blood removal (phlebotomy). People with hemochromatosis can also control their iron absorption with dietary changes. [...]
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Several risk factors are associated with an increased chance of developing hereditary hemochromatosis: Family history An individual’s family history can offer clues about the chances of developing hemochromatosis. People with a parent or sibling who have a confirmed diagnosis of hemochromatosis are more likely to develop hemochromatosis. People with a family history of premature death [...]
Hemochromatosis is treated by removing excess iron from the body to bring iron levels back down to normal. Phlebotomy The most common treatment method for hemochromatosis is iron reduction through phlebotomy, which is regular blood removal or donation. Phlebotomy is generally divided into two stages, initial treatment and maintenance treatment for hemochromatosis. For initial hemochromatosis [...]
Hemochromatosis diagnosis is based on a combination of laboratory and genetic testing results. Genetic testing is used to confirm the diagnosis of hemochromatosis, and laboratory tests such as blood iron tests and liver biopsy can be useful in determining the progression of the disease and the types of treatment required. GENETIC TESTING Genetic testing of [...]
Although the genetic mutation that causes hereditary hemochromatosis is present at birth, the signs and symptoms of hemochromatosis do not normally appear until later in life, as it takes time for iron to slowly accumulate in tissues and organs. Early signs and symptoms of hemochromatosis are nonspecific, making it difficult to diagnose against other common [...]
There are four general types of hemochromatosis, which are classified in regards to the age of onset, genetic causes and mode of inheritance. Type 1 hemochromatosis is the most classic and common form of hereditary hemochromatosis. The age of onset is about 30 and 50 years old for males, and 10 to 15 years after [...]
Hereditary hemochromatosis, also called iron overload disorder, is a genetic disorder that causes the body to absorb extra amounts of iron from the diet. However, the human body cannot get rid of the extra iron. The excess iron accumulates in the organs over time, which causes iron overload and eventually leading to tissue and organ [...]